Lupus (The SLE)

What is lupus?

When it's operating commonly, the body's system kills germs and "bad" cells that would be converted into cancer. Sometimes, rather than killing solely dangerous cells, one thing goes wrong and also the system starts to attack healthy cells. That is called an autoimmune response. It is what happens in lupus. In alternative words, if you have got lupus, your body is attacking itself. Dr. Ashok Gupta performs as SLE doctor in Bhopal for more than 32 years.

What are the symptoms of lupus?

People with lupus can:

• Feel tired or weak
• Lose or gain weight
• Get fevers
• Get headaches
• Get a rash on their nose and cheeks formed sort of a butterfly, particularly if they pay time within the sun
• Lose some hair
• Get chest pain
• Have trouble breathing
• Bruise easily
• Have joint pain and stiffness
• Have swelling in the hands, feet, belly, or around the eyes
• Have an excretory product that appears brown (tea-colored) or foamy
• Get sores in the mouth
• Get cold fingers or toes that turn pale or blue

Lupus may also build it exhausting to suppose clearly, and it will build folks feel anxious and unhappy. That is partly as a result of the unwellness attacks the brain, and part as a result of the unwellness is difficult to touch upon.

Can I do anything on my own to feel better?

Yes. It will facilitate to eat a healthy diet, choked with fruits and vegetables. It's also vital to remain active, even though you are doing not feel well. If you rest an excessive amount of, your muscles can get weak and you may feel even worse later. Also, any time a doctor or nurse gives you medicine, make sure he or she knows you have lupus. Some medicines make lupus worse. It is important that you not take them.

What are the treatments for lupus?

There square measure medicines that may ease lupus symptoms, decrease the reaction response or both. These medicines include:

• NSAIDs, such as ibuprofen (sample complete name: Brufen) or NSAID (sample complete name: Naprosyn), which may ease joint pain
• Medicines referred to as "hydroxychloroquine" or "chloroquine," that was originally created to treat protozoal infection, however, may also facilitate with lupus
• Steroids and related medicines, which partly "turn off" the immune system, and can help with many of the problems caused by lupus (these are not the same as the steroids some athletes take illegally)

Steroids will do a great deal of excellent because they control the disease. But they will conjointly cause issues of their own. For instance, steroids can cause weight gain, make bones weak, or make diabetes worse (or even cause diabetes).

What if I want to get pregnant?

Women with lupus square measure additional seemingly than alternative ladies to possess issues with gestation. But they can have healthy babies.
If you'd wish to get pregnant, speak together with your doctor or nurse before you begin making an attempt to induce pregnantly. There square measure ways that for you to scale back the probabilities of getting issues. For example, it is significant that you wait pending you have not had lupus indication for 5- 6 months.

How will lupus affect my life?

You will have lupus for the rest of your life. It might be severe, or it'd be delicate. Either way, doctors and nurses nowadays apprehend a great deal regarding the way to handle the unwellness. You are likely to live a long time. And you may even realize that your symptoms depart for long periods.



Systemic lupus (also called lupus or SLE) could be a chronic disease that may have an effect on varied components of the body. Lupus is associate reaction condition, which means that your body's system attacks your own tissues, thinking that they're foreign. This can result in pain, swelling, and injury to organs like the kidneys. The cause of lupus is not clear.

People with lupus typically have unwellness flares, within which symptoms worsen, followed by an amount of remission, in which symptoms improve. Lupus is delicate in some folks and is severe in others. However, treatments square measure accessible to scale back symptoms, reverse inflammation, and minimize organ damage.


The exact cause of lupus is not known. A person with lupus most likely inherits the danger from one or each folk, although symptoms usually don't develop until young adulthood or later.


Symptoms of general lupus (lupus, SLE) are often caused by inflammation, which can affect the whole or parts of the body. Other lupus symptoms square measure caused by inflammation and/or injury to a specific organ system.

Whole body symptoms — will embrace fatigue and weight loss.

Organ-related symptoms embrace roseola following sun exposure and simple bruising thanks to decreased numbers of platelets within the blood.

Fatigue — Fatigue is that the commonest symptom of lupus, and sometimes the most debilitating. Almost everybody with lupus experiences fatigue, even when there are no other symptoms.
Fatigue is also caused by lupus itself or by underlying problems, such as depression, unhealthy habits stress, anemia, use of certain medications, other health problems, lack of exercise, and, in particular, difficulty sleeping.
Problems with sleep square measure typically treated with medication and an exercise program can improve energy levels. Weight changes — SLE will result in each weight loss and weight gain. Unintentional weight loss is often due to:

• Decreased appetite
• The side effects of medications
• Gastrointestinal disease

Weight gain is usually due to one of 2 factors:
• Salt and water retention related to uropathy
• raised craving related to the utilization of steroids or alternative medications

Fever — many of us with SLE get frequent fevers once their unwellness flares. Fever is outlined as a temperature over 100°F.

Specific organ symptoms — SLE can affect many organs of the body, resulting in a variety of symptoms.

Joint pain and stiffness — Joint pain and stiffness occur in most individuals with lupus, and these are often the earliest symptoms. The pain and stiffness tend to maneuver from one a part of the body to a different and doesn't sometimes have an effect on each side of the body within the same means. Only a few joints are affected at any Tim). Typical joints include the fingers, wrists, and knees. Joints may be swollen and warm ("arthritis").

Skin changes — the simple fraction of individuals with disseminated lupus erythematosus have skin issues at a while. The most common may be a rash, known as the "butterfly rash"; this appears as redness over the cheeks and nose after being in the sun. The rash sometimes lasts solely many days however typically comes back.

Discoid lupus causes raised red areas ("plaques") and scars on the skin. Picture A shows a human ear, and picture B shows a person's cheek.

Some individuals develop circular patches of raised, scaly skin (called discoid lesions), which have a tendency to scar. Hair loss (alopecia) is common, but baldness is not. Many people develop ulcers within the mouth, which are usually painless.

The "Raynaud phenomenon" may be a condition that causes blood vessels within the fingers and toes to slender in response to cold temperatures, emotional stress, and/or cigarette smoking. As the blood vessels slender, less blood flows to the realm, causing the fingers or toes to become pale and then blue, purple, and/or read .. Raynaud phenomenon is a frequent problem in patients with SLE. However, most of the people World Health Organization have Raynaud don't have lupus. During a Raynaud attack, the fingers (or toes) become suddenly pale or white (panel A) as the blood vessels constrict. They might then flip a purple or blue color (panel B), which means there is less blood than normal flowing to the fingers. The thumb is often not affected.

During a Raynaud attack, the fingers (or toes) become suddenly pale or white (panel A) as the blood vessels constrict.

Light sensitivity — Between sixty and 100% of individuals with lupus area unit sensitive to ultraviolet (UV) light-weight. This "photosensitivity" causes the person to develop a rash once exposure to ultraviolet from the sun or fluorescent lights. Some people are also sensitive to UVA radiation (from sunlight). Glass protects individuals sensitive to UVB (from sunlight or fluorescent light) but only partially protects those sensitive to UVA. Blonde, blue-eyed, fair-skinned individuals area unit far more light-sensitive than brunettes or individuals with darker skin.

If you're sensitive to daylight, you can do the following to minimize UV exposure:
• Use a cream with a sun-protection issue (SPF) of fifty or bigger a day, even if you don't plan to spend a lot of time outdoors. The cream ought to be applied thirty to the hour before going outside and will be reapplied each four to 6 hours.
• Avoid sun exposure throughout the noon (between ten AM and four PM).

• Avoid medications which will cause sensitivity (your doctor or nurse will confer with you concerning this if you've got questions about your medications).

Kidneys — Changes in urinary organ perform area unit common in individuals with lupus. These changes sometimes develop throughout the primary few years of the ill health. Monitoring for changes in urinary organ perform with excreta and blood tests will facilitate to discover these changes.
• Lupus will cause inflammation of the filtering device within the kidneys (the glomerulus); this is often known as nephritis or lupus renal disorder. Damage to the glomeruli will stop the kidneys from filtering wastes from the blood.
• ab initio, the kidneys could "leak" supermolecule from the blood into the excreta. When harsh, this can reason water maintenance, a bulge in the feet and lower legs, and additionally alter referred to as the nephrotic condition.
Left untreated, lupus nephritis can lead to permanent scarring in the kidneys. If the kidneys area unit too broken to filter the blood properly, you will need dialysis or a kidney transplant. Providentially, action to prevent or diminish lupus-related kidney syndrome is obtainable.

Digestive system — The systema digestorium stricken by medications often wont to treat lupus, including glucocorticoids and NSAIDs. These medicines will cause the symptom, or, less commonly, stomach ulcers.

Lungs — — the variety of respiratory organ diseases will occur in individuals with Lupus;
Pain with breathing – inflammatory disease may be a sort of pain that gets worse once you take a deep breath. This can occur if there's inflammation of the liner covering the lungs and inside the chest.
Shortness of breath – Shortness of breath will occur because of many totally different issues. Collection of fluid within the area around the respiratory organs (called serous membrane effusion) will interfere with enlargement of the lung. Inflammation of the air sacs of the respiratory organ (pneumonitis) or dysfunction and scarring of the supporting tissues between the air sacs (interstitial respiratory organ disease) will cause issue respiratory. Heart — There area unit a spread of symptoms which will develop if lupus affects the center or blood vessels:

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