Oral steroids, also known as "glucocorticoids," are pills you take by
mouth to treat a wide range of medical conditions. These include autoimmune conditions (such
as rheumatoid arthritis), allergic reactions, and flares of asthma or chronic obstructive
pulmonary disease (also called "COPD"). Steroid medicines can also be given through an "IV" if you cannot swallow pills or you are in the hospital. An IV is a thin tube that goes into a vein.
This article is for people who need to take oral steroids for a short time.
Oral steroid medicines arenot the same as the steroids some athletes take illegally to build
muscle.
Commonly used oral steroids includeprednisone (sample brand: Omnacortil),prednisolone(sample brand: Orapred),dexamethasone (sample brand: Decadron), andmethylprednisolone (sample brand: Medrol). These medicines come as pills and liquids.
Oral steroids treat a wide variety of medical conditions. They include:
• Autoimmune conditions, such as rheumatoid arthritis, Crohn disease, or lupus–
Some medical conditions happen when the body's infection-fighting system, called the
"immune system," attacks healthy tissues and organs. This is called an "autoimmune
response." Oral steroid medicines can help reduce or prevent this attack.
• Asthma, COPD, or gout flare – Oral steroids are used to reduce swelling and improve
breathing for people who are having a severe flare or "attack" of asthma or COPD. (COPD
is short for "chronic obstructive pulmonary disease," a lung disease that makes it hard to
breathe.) Oral steroids can also reduce pain and swelling in people with attacks of gout.
• Nausea and vomiting – Oral steroids are sometimes used with other medicines to
prevent nausea and vomiting due to chemotherapy.
• Prevent organ rejection – Oral steroids are also used with other medicines to keep your
immune system from attacking a transplanted kidney or other transplanted organ.
• Severe allergic reaction – Oral steroids can be used for a short time to help with a
severe allergic reaction, for example due to poison ivy. You might take a smaller dose each
day for several days, and then stop.
Follow the instructions your doctor gives you. People usually take oral steroids with breakfast or another meal so the medicine does not cause an upset stomach.
Taking oral steroids for less than 3 weeks is not
likely to cause any serious side effects. Mild side effects that can happen with short-term use
include upset stomach, increased appetite, and trouble sleeping. Talk to your doctor if you have
any of these side effects and they bother you.
More serious effects can occur if your condition requires you to take oral steroids for a long time
or at high doses. These can include:
• Thin skin
• Eye problems (such as glaucoma or cataracts)
• High blood pressure
• Heart problems
• Osteoporosis and other bone problems
• Growth problems in children and adolescents
• High blood sugar or diabetes
• Higher chance of getting infections
Your doctor will give you the lowest dose for the shortest possible time. This lowers the risk of side effects. If you take steroid medicines for a long time, you will need regular exams and tests.
Always take your steroid medicine exactly
the way your doctor tells you to.
If you need to take oral steroids for more than 3 weeks, carry a card that lists the name and
dose of the steroid you take. Show this card to anyone who treats you. You should also talk to
your doctor or nurse to make sure you get all the vaccines you need. That's because taking
steroid medicines for a long time can increase your chance of getting certain infections.
If your condition changes, or you get sick or need surgery when you have been taking oral
steroids for more than 3 weeks, your doctor might adjust your dose. If you need to stop taking
your steroid medicine, he or she will explain how to gradually decrease the dose. This is called
"tapering."
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